An early morning house fire has destroyed a Point Cook home.

CFA crews were called to the Catalina Court home around 5-45 this morning, finding the home well alight.

They managed to bring the blaze under control in just over half-an-hour.

The cause is not thought to be suspicious, but fire investigators are trying to determine the cause.

Jayson Hirt from the CFA says the two occupants managed to escape the house through a front window, and have been taken to hospital suffering smoke inhalation.

And he says smoke detectors were working in the home.

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Image: a Point Cook home destroyed in an early morning blaze [J McLennan]